Abstract:

Article is devoted to the analysis of life, scientific and practical activities of professor Leonid Semenovich Zingerman - one of pioneers in diagnostic and interventional radiology in Russia, the founder of scientific and practical school in the sphere of diagnostic and interventional radiology in urgent situations. The article shows the role of professor Zingerman in development of radiological and diagnostic interventions in cardiac surgery neurosurgery, abdominal surgery and gynecology on the base of Bakoulev Scientific Center for Cardiovascular Surgery (1958-1977) and Scientific and Research Institute of emergency medicine (1977-1992).

Abstract:

Aim: was to evaluate efficiency of stents-grafts in treatment of cerebral aneurysms.

Materials and methods: for the period of 2001-2012 implantation of stent-grafts was performedm 10 patients with cerebral aneurysms. Indications for implantation: huge or giant aneurysms; wide«neck» of aneurysm; difficult localization for neurosurgical techniques; absence of significant tortuosity of artery that could interfere successful stent delivery All patients underwent examination:

MSCT-angiography, MRI, cerebral angiography To predict possible stent thrombosis we performed angiographic tests with pinching of pathological artery and contrasting of opposite artery Then we assessed blood-flow of anterior and posterior communicating arteries and also changes in neurological status. Unsatisfactory condition of collateral blood-flow - was not a contraindication for stenting. In 8 patient, aneurysms were localized in internal carotid artery, and in 2 patients in the vertebrobasilar artery In 3 cases implantation of stent-graft was proceeded in acute period of hemorrhage; that caused late disaggregant therapy (immediately after implantation, drugs were injected through nasogastric tube instead of 4-5 days of preoperative treatment).

Results: exclusion of the aneurysm from the blood-flow was reached 100% of cases. In one case, implantation of micro-coils was necessary due to inability to cover the whole neck of the aneurysm because of tortuosity of artery In 1 case we had thrombosis of stent in vertebral artery with spreading of thrombosis on basilar artery with development of ischemic stroke and further death.

Conclusion: use of stent-grafts for exclusion of huge and giant aneurysms from cerebral blood- flow is a highly effective method.

References

1.     Zeb M., McKenzie D.B., Scott P.A., Talwar S. Treatment of coronary aneurysms with covered stents: a review with illustrated case. J. Invasive Cardiol. 2012; 24 (9): 465-469.

2.     Briguori C., Nishida T., Anzuini A. et al. Emergency polytetrafluoroethylene-covered stent implantation to treat coronary ruptures. Circulation. 2000; 102 (25): 30283031.

3.     Saatci I,.Cekirge H.S., Ozturk M.H. et al. Treatment of internal carotid artery aneurysms with a covered stent: experience in 24 patients with midterm follow-up results. AJNR Am. J. Neuroradiol. 2004; 25 (10): 1742-1749.

4.     Hirurgija anevrizm golovnogo mozga. V 3 tomah. T. 1. Pod red. V.V. Krylova [Brain aneurysms surgery. In three volumes. Vol. 1. Edited by V.V. Krylov]. Moscow. 2012; 432S [In Russ].

5.    Tissen T.P., Jakovlev S.B. Bocharov A.V. Buharin E.Ju. Ispol'zovanie stent-grafta v jendovaskuljarnoj nejrohirurgii. Voprosy nejrohirurgii im. N.N. Burdenko [The use of stent-graft in endovascular neurosurgery]. 2006; 2: 53-56. [In Russ].

6.     Vulev I., Klepanec A., Bazik R. et al. Endovascular treatment of internal carotid and vertebral artery aneurysms using a novel pericardium covered stent. Interv. Neuroradiol. 2012; 18 (2): 164-171.

7.     Greenberg E., Katz J.M., Janardhan V. et al. Treatment of a giant vertebrobasilar artery aneurysm using stent grafts. Case report. J. Neurosurg. 2007; 107 (1): 165-168.

8.     Li M.H., Li YD., Tan H.Q. et al. Treatment of distal internal carotid artery aneurysm with the willis covered stent: a prospective pilot study. Radiology. 2009; 253 (2): 470-477.

9.     Chalouhi N., Tjoumakaris S., Gonzalez L.F. et al. Coiling of large and giant aneurysms: complications and long-term results of 334 cases. AJNR Am. J. Neuroradiol. 2014; 35 (3): 546-452.